Vadodara’s MS University Researchers Develop New Drug Compound to Target Alzheimer’s Disease, Receive Patent

Researchers from the Faculty of Pharmacy at Maharaja Sayajirao University (MSU), Vadodara, have developed a new drug compound that may help fight Alzheimer’s disease. The compound has the ability to block an enzyme linked to the destruction of brain cells. The research has also received a patent from the government’s patent office.

The research was carried out by Dr. Prashant Murumkar and research scholar Omkumar Prajapati. They developed a compound called Vicinal Diaryl Pyrazole, which can block an enzyme known as Monoamine Oxidase (MAO). This enzyme is linked to the production of harmful substances that can damage neurons, or brain cells.

Lab Tests Show Promising Results

According to the researchers, laboratory tests showed that the new compound could block the targeted enzyme. It also showed antioxidant properties, which may help protect cells from damage. No side effects were observed during these tests. However, further research is needed to confirm its safety and effectiveness.

The researchers said that the compound must now undergo clinical trials to check how it works in the human body. These trials will help determine its safety, suitable dosage and effectiveness in patients. It is not yet an approved medicine.

Dementia Cases Expected to Rise Worldwide

According to figures shared by the researchers, around 55 million people worldwide and approximately 8.8 million people in India are living with dementia. Alzheimer's disease accounts for nearly 60 to 70% of dementia cases. The number of people affected by dementia is expected to increase significantly in the coming decades.

Dementia affects a person's memory, thinking and ability to perform daily activities. Alzheimer's disease is one of its most common causes and usually leads to gradual memory loss. The researchers hope their work will help in developing better treatment options in the future.