UK woman loses all four limbs after rare sepsis infection linked to dog’s lick

A 56-year-old Indian-origin woman in the UK underwent multiple amputations after developing a rare but severe infection believed to have been triggered when her pet dog licked a small cut on her leg, as per reports.
Manjit Sangha, a former pharmacy worker who had previously been in good health, was hospitalised in July last year after suddenly falling ill. Within days, her condition reportedly deteriorated rapidly, and she slipped into a coma. Doctors later diagnosed an aggressive form of sepsis — a life-threatening condition caused by the body’s extreme response to infection.
As per reports, the infection progressed with unusual speed. Both her legs below the knees and both hands had to be amputated in order to save her life. She also suffered six cardiac arrests during her treatment but survived each episode.

Sangha was discharged from hospital last week and has returned home. She and her husband are now seeking to raise funds for prosthetic limbs to help restore some degree of mobility and independence.
Reports citing medical experts say that while infections linked to dog saliva are extremely rare, they are medically possible. Dogs naturally carry bacteria in their mouths, including Capnocytophaga, which generally causes no harm but can enter the bloodstream through cuts or abrasions. Other bacteria sometimes present include Pasteurella, Staphylococcus and Streptococcus.
Sepsis remains a major public health challenge in India; it reportedly accounts for 29 lakh deaths annually and nearly three in ten deaths overall. Pneumonia, urinary tract infections and abdominal infections are among the most common triggers.
According to reports, experts also highlight the growing threat of multidrug-resistant bacteria, poor sanitation and inappropriate antibiotic use as contributing factors to high mortality.
When bacteria enter the bloodstream, the immune response can become uncontrolled, leading to widespread inflammation, clotting disorders, impaired circulation and organ failure. In severe cases, tissue death may necessitate amputation.
Early symptoms of sepsis can include fever, chills, vomiting, muscle aches, fatigue, a rapid heartbeat, breathlessness, confusion and skin discolouration or rashes. As the condition advances, blood pressure may fall sharply, leading to septic shock.
Doctors stress that basic precautions can significantly reduce risk. Open wounds should not be exposed to pet saliva, and any bites or scratches should be washed thoroughly with soap and water, followed by antiseptic application. Medical attention should be sought promptly if unusual symptoms develop.
People with chronic illnesses or weakened immunity are advised to exercise particular caution, as early diagnosis and timely antibiotic treatment are crucial in preventing severe complications.

